Low/High-intensity Transcranial Focused Ultrasound (LTFU)

Transcranial Focused Ultrasound (tFUS) is a non-invasive technology that delivers concentrated ultrasound energy through the skull to precisely target areas within the body. It is classified by intensity:

• Low-Intensity tFUS:

  • Used for neuromodulation and functional regulation, influencing activity in targeted regions without causing damage.

  • Being explored for various applications, including mental health, pain management, and neurological conditions.

  • Offers high spatial accuracy, deep penetration, and non-destructive interaction with tissue.

• High-Intensity tFUS:

  • Used for precise thermal ablation or to open biological barriers like the blood-brain barrier.

  • Suitable for non-invasive treatment of conditions such as tumors, tremors, or drug delivery enhancement.

  • Often combined with imaging (e.g., MRI) for real-time guidance and monitoring.

This technology represents a promising frontier in targeted, non-invasive therapy across medical fields.